Sensor materials for the detection of human neutrophil elastase and cathepsin G activity in wound fluid.

@article{Hasmann2011SensorMF,
  title={Sensor materials for the detection of human neutrophil elastase and cathepsin G activity in wound fluid.},
  author={Andrea Hasmann and Ulrike Gewessler and Elisabeth Hulla and Konstantin P Schneider and Barbara Binder and Antonio Francesko and Tzanko Tzanov and Michael Valentin Schintler and Job van der Palen and Georg M. Guebitz and Eva Wehrschuetz-Sigl},
  journal={Experimental dermatology},
  year={2011},
  volume={20 6},
  pages={508-13}
}
Human neutrophil elastase (HNE) and cathepsin G (CatG) are involved in the pathogenesis of a number of inflammatory disorders. These serine proteinases are released by neutrophils and monocytes in case of infection. Wound infection is a severe complication regarding wound healing causing diagnostic and therapeutic problems. In this study we have shown the potential of HNE and CatG to be used as markers for early detection of infection. Significant differences in HNE and CatG levels in infected… CONTINUE READING