Sensitized increase of period gene expression in the mouse caudate/putamen caused by repeated injection of methamphetamine.

@article{Nikaido2001SensitizedIO,
  title={Sensitized increase of period gene expression in the mouse caudate/putamen caused by repeated injection of methamphetamine.},
  author={Takato Nikaido and Masashi Akiyama and Takahiro Moriya and Shigenobu Shibata},
  journal={Molecular pharmacology},
  year={2001},
  volume={59 4},
  pages={894-900}
}
Methamphetamine (MAP) causes the sensitization phenomena not only in MAP-induced locomotor activity, dopamine release, and Fos expression, but also in MAP-induced circadian rhythm. Cocaine-induced sensitization is reportedly impaired in Drosophila melanogaster mutant for the Period (Per) gene. Thus, sensitization may be related to induction of the Per gene. A rapid induction of mPer1 and/or mPer2 in the suprachiasmatic nucleus after light exposure is believed to be necessary for light-induced… CONTINUE READING
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Basal hyperactivity and behavioral sensitization to cocaine in Clock mutant mice

  • K Sidiropoulou, DC Cooper, L Baker, MH Vitaterna, JS Takahashi, FJ White
  • Soc Neurosci Abstr
  • 2000
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