Sensitization to the pollen pan-allergen profilin. Is the detection of immunoglobulin E to multiple homologous proteins from different sources clinically useful?

BACKGROUND Profilin is a highly conserved protein regarded as a pan-allergen in pollen and vegetable food. Homologous proteins from different sources are highly cross-reactive. OBJECTIVE To assess whether detecting immunoglobulin (Ig) E to multiple profilins from different sources is clinically more useful than detecting IgE to a single representative… CONTINUE READING