Sensitization to TRAIL-induced apoptosis and modulation of FLICE-inhibitory protein in B chronic lymphocytic leukemia by actinomycin D

@article{Olsson2001SensitizationTT,
  title={Sensitization to TRAIL-induced apoptosis and modulation of FLICE-inhibitory protein in B chronic lymphocytic leukemia by actinomycin D},
  author={Anna S. B. Olsson and Terre Diaz and Miguel Aguilar-Santelises and Anders {\"O}sterborg and Fredrik Celsing and Mikael Jondal and L M Osorio},
  journal={Leukemia},
  year={2001},
  volume={15},
  pages={1868-1877}
}
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potent activator of the cell death pathway and exerts tumoricidal activity in vivo with minimal toxicity. In order to investigate the therapeutic potential of TRAIL in B chronic lymphocytic leukemia (B-CLL) we have analyzed the expression of TRAIL receptors (TRAIL-Rs) in leukemic cells… CONTINUE READING