Sensitization of the trigeminal sensory system during different stages of the rat estrous cycle: implications for menstrual migraine.

@article{Martin2007SensitizationOT,
  title={Sensitization of the trigeminal sensory system during different stages of the rat estrous cycle: implications for menstrual migraine.},
  author={Vincent T. Martin and James M. Lee and Michael M Behbehani},
  journal={Headache},
  year={2007},
  volume={47 4},
  pages={552-63}
}
OBJECTIVES To determine if the sensitization of the trigeminal system changes after dural activation of the trigeminal nerve during different stages of the rat estrous cycle. BACKGROUND The specific mechanisms through which ovarian hormones trigger menstrual migraine are currently unknown. Past animal studies have suggested that the response properties of the trigeminal nucleus caudalis (TNC) may change during the different phases of the rat estrous cycle, but none have been performed in an… CONTINUE READING