Sensitivityin vivo of centralα 2-and opiate receptors after chronic treatment with various antidepressants

@article{ScuveMoreau1982SensitivityinVO,
  title={Sensitivityin vivo of centralα 2-and opiate receptors after chronic treatment with various antidepressants},
  author={Dr. Jacqueline J. Scuv{\'e}e-Moreau and Torgny H. Svensson},
  journal={Journal of Neural Transmission},
  year={1982},
  volume={54},
  pages={51-63}
}
Recent studies suggest that the antidepressant activity could be explained by gradually developing modifications in the sensitivity of some central monoaminergic receptors. As concernsα 2-receptors, some largely indirect informations suggest that a subsensitivity develops following chronic treatment with desipramine or imipramine. However it is not clear whether this effect is shared by other antidepressants. In view of the important role of these receptors in the regulation of noradrenergic… CONTINUE READING

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Contribution exp&imentale ~ l'6tude du mode d'action des substances antid4pressives

Scuv, J. -Moreau
  • Universit4 de Lihge, Thhse,
  • 1981