Sensitivity to rewarding or aversive effects of methamphetamine determines methamphetamine intake.

@article{Shabani2011SensitivityTR,
  title={Sensitivity to rewarding or aversive effects of methamphetamine determines methamphetamine intake.},
  author={Shkelzen Shabani and Carrie S. McKinnon and Cheryl Reed and Christopher L. Cunningham and Tamara J Phillips},
  journal={Genes, brain, and behavior},
  year={2011},
  volume={10 6},
  pages={625-36}
}
Amphetamines have rewarding and aversive effects. Relative sensitivity to these effects may be a better predictor of vulnerability to addiction than sensitivity to one of these effects alone. We tested this hypothesis in a dose-response study in a second replicate set of mouse lines selectively bred for high vs. low methamphetamine (MA) drinking (MADR). Replicate 2 high (MAHDR-2) and low (MALDR-2) MA drinking mice were bred based on MA consumption in a two-bottle choice procedure and examined… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Topics from this paper.
21 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…