Sensitivity to instrumental contingency degradation is mediated by the entorhinal cortex and its efferents via the dorsal hippocampus.

@article{Corbit2002SensitivityTI,
  title={Sensitivity to instrumental contingency degradation is mediated by the entorhinal cortex and its efferents via the dorsal hippocampus.},
  author={Laura H. Corbit and Sean B. Ostlund and Bernard W. Balleine},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2002},
  volume={22 24},
  pages={10976-84}
}
Previous studies have shown that electrolytic lesions of the dorsal hippocampus render the instrumental performance of rats insensitive to selective degradation of the action-outcome contingency (Corbit and Balleine, 2000). In the present experiments, we sought to replicate this finding and to examine the effects of excitotoxic lesions. In the first three experiments, rats with either electrolytic or NMDA lesions of the dorsal hippocampus and sham-lesioned controls were trained to press two… CONTINUE READING