Sensitivity to inhibition by beta-chemokines correlates with biological phenotypes of primary HIV-1 isolates.

@article{Jansson1996SensitivityTI,
  title={Sensitivity to inhibition by beta-chemokines correlates with biological phenotypes of primary HIV-1 isolates.},
  author={M{\aa}rten Jansson and Mikul{\'a}{\vs} Popovi{\vc} and Anders Karlsson and Fiorenza Cocchi and Paolo Emilio Rossi and Jan Albert and Hans Wigzell},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1996},
  volume={93 26},
  pages={15382-7}
}
Primary HIV-1 isolates were evaluated for their sensitivity to inhibition by beta-chemokines RANTES (regulated upon activation, normal T-cell expressed and secreted), macrophage inflammatory protein 1 alpha (MIP-1 alpha), and MIP-1 beta. Virus isolates of both nonsyncytium-inducing (NSI) and syncytium-inducing (SI) biological phenotypes recovered from patients at various stages of HIV-1 infection were assessed, and the results indicated that only the isolates with the NSI phenotype were… CONTINUE READING

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