Sensitivity of the female rat to olanzapine-induced weight gain—Far from the clinic?

  title={Sensitivity of the female rat to olanzapine-induced weight gain—Far from the clinic?},
  author={K. Weston-Green and Xu-Feng Huang and C. Deng},
  journal={Schizophrenia Research},
  • K. Weston-Green, Xu-Feng Huang, C. Deng
  • Published 2010
  • Psychology, Medicine
  • Schizophrenia Research
  • Dear Editor, The recent paper by Chintoh and colleagues (2008) reporting olanzapine-induced dysfunction in glucose metabolism, enhanced visceral fat and reduced locomotor activity in female rats was highly interesting as it illustrated olanzapine’s ability to replicate aspects of metabolic dysfunction in the rodent model in a similar manner to the human scenario. However, contrary to previous reports in the rat and the clinic, the authors reported no change in body weight or food intake… CONTINUE READING


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