Sensitivity of a modified ACT test to levels of bivalirudin used during cardiac surgery.

@article{Zucker2005SensitivityOA,
  title={Sensitivity of a modified ACT test to levels of bivalirudin used during cardiac surgery.},
  author={Marcia L. Zucker and Andreas M. Koster and J. Guillen Prats and Frank M Laduca},
  journal={The journal of extra-corporeal technology},
  year={2005},
  volume={37 4},
  pages={
          364-8
        }
}
Assessment of anticoagulation status during cardiac surgery can be valuable for novel therapeutics, including direct thrombin inhibitors. The ecarin clotting time (ECT) has been reported to be sensitive for monitoring of bivalirudin in cardiac surgery but is not commercially available. The activated clotting time (ACT), commonly used for heparin monitoring, may display a lack of sensitivity to alternative anticoagulants when used in on-pump cardiac surgery. Both the ACT and ECT have been… CONTINUE READING

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