Sensitivity of Human Cancer Cells to the New Anticancer Ribo‐nucleoside TAS–106 Is Correlated with Expression of Uridine‐cytidine Kinase 2

@inproceedings{Shimamoto2002SensitivityOH,
  title={Sensitivity of Human Cancer Cells to the New Anticancer Ribo‐nucleoside TAS–106 Is Correlated with Expression of Uridine‐cytidine Kinase 2},
  author={Yuji Shimamoto and Katsuhisa Koizumi and Hiroyuki Okabe and Hiromi Kazuno and Yuko Murakami and Fumio Nakagawa and Akira Matsuda and Takuma Sasaki and Masakazu Fukushima},
  booktitle={Japanese journal of cancer research : Gann},
  year={2002}
}
TAS-106 [1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine] is a new anticancer ribo-nucleoside with promising antitumor activity. We have previously presented evidence suggesting that the TAS-106 sensitivity of cells is correlated with intracellular accumulation of the triphosphate of TAS-106, which may be affected both by cellular membrane transport… CONTINUE READING