Sensitivity improvement of transverse relaxation-optimized spectroscopy.

@article{Rance1999SensitivityIO,
  title={Sensitivity improvement of transverse relaxation-optimized spectroscopy.},
  author={Mark Rance and J Patrick Loria and Palmer AG3rd},
  journal={Journal of magnetic resonance},
  year={1999},
  volume={136 1},
  pages={
          92-101
        }
}
Procedures are described for significantly improving the sensitivity of the recently proposed TROSY (transverse relaxation-optimized spectroscopy) experiment (K. Pervushin et al., 1997, Proc. Natl. Acad. Sci. USA 94, 12366-12371). The TROSY experiment takes advantage of destructive interference between dipolar and chemical shift anisotropy relaxation mechanisms to achieve substantial reductions in resonance linewidths in heteronuclear correlation spectra; the effect is significant particularly… CONTINUE READING

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