Sensitivity and specificity of liver function tests in the detection of parenteral nutrition-associated cholestasis.

@article{Nanji1985SensitivityAS,
  title={Sensitivity and specificity of liver function tests in the detection of parenteral nutrition-associated cholestasis.},
  author={AminA. Nanji and Frank H. Anderson},
  journal={JPEN. Journal of parenteral and enteral nutrition},
  year={1985},
  volume={9 3},
  pages={
          307-8
        }
}
We carried out a study to determine which of the liver function tests was the most sensitive and/or specific in detecting parenteral nutrition associated cholestasis. The tests utilized were alkaline phosphatase, gamma-glutamyl transpeptidase, cholylglycine, sulfolithocholylglycine, and bilirubin. Fifty-nine patients with no prior evidence of liver dysfunction were studied. We found gamma-glutamyl transpeptidase to be the most sensitive (89.5%) and also the least specific (61.9% specificity… CONTINUE READING
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