Sensitivity and specificity of intrathecal fluorescein and white light excitation for detecting intraoperative cerebrospinal fluid leak in endoscopic skull base surgery: a prospective study.

@article{Raza2016SensitivityAS,
  title={Sensitivity and specificity of intrathecal fluorescein and white light excitation for detecting intraoperative cerebrospinal fluid leak in endoscopic skull base surgery: a prospective study.},
  author={Shaan M Raza and M. A. Nishara Banu and Angela M Donaldson and Kunal S. Patel and Vijay Karan Singh Anand and Theodore H. Schwartz},
  journal={Journal of neurosurgery},
  year={2016},
  volume={124 3},
  pages={621-6}
}
OBJECTIVE The intraoperative detection of CSF leaks during endonasal endoscopic skull base surgery is critical to preventing postoperative CSF leaks. Intrathecal fluorescein (ITF) has been used at varying doses to aid in the detection of intraoperative CSF leaks. However, the sensitivity and specificity of ITF at certain dosages is unknown. METHODS A… CONTINUE READING