Sensitivity and reproducibility of a new fast 3D segmentation technique for clinical MR-based brain volumetry in multiple sclerosis

@article{Lukas2004SensitivityAR,
  title={Sensitivity and reproducibility of a new fast 3D segmentation technique for clinical MR-based brain volumetry in multiple sclerosis},
  author={Carsten Lukas and Horst K. Hahn and Barbara Bellenberg and Jan Rexilius and Gebhard Schmid and Sebastian K. Schimrigk and Horst Przuntek and Odo Koester and Heinz-Otto Peitgen},
  journal={Neuroradiology},
  year={2004},
  volume={46},
  pages={906-915}
}

• Carsten Lukas, Horst K. Hahn, +6 authors Heinz-Otto Peitgen
• Published in Neuroradiology 2004
• DOI:10.1007/s00234-004-1282-3

Fast, reliable and easy-to-use methods to quantify brain atrophy are of increasing importance in clinical studies on neuro-degenerative diseases. Here, ILAB 4, a new volumetry software that uses a fast semi-automated 3D segmentation of thin-slice T1-weighted 3D MR images based on a modified watershed transform and an automatic histogram analysis was evaluated. It provides the cerebral volumes: whole brain, white matter, gray matter and intracranial cavity. Inter- and intra-rater reliability and… CONTINUE READING

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