Sensitivity, Specificity, PPV, and NPV for Predictive Biomarkers.

  • Richard Simon
  • Published 2015 in Journal of the National Cancer Institute

Abstract

Molecularly targeted cancer drugs are often developed with companion diagnostics that attempt to identify which patients will have better outcome on the new drug than the control regimen. Such predictive biomarkers are playing an increasingly important role in precision oncology. For diagnostic tests, sensitivity, specificity, positive predictive value, and… (More)
DOI: 10.1093/jnci/djv153

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