Sensitive time-windows for susceptibility in neurodevelopmental disorders

@article{Meredith2012SensitiveTF,
  title={Sensitive time-windows for susceptibility in neurodevelopmental disorders},
  author={Rhiannon M. Meredith and Julia Dawitz and Ioannis Kramvis},
  journal={Trends in Neurosciences},
  year={2012},
  volume={35},
  pages={335-344}
}
Many neurodevelopmental disorders (NDDs) are characterized by age-dependent symptom onset and regression, particularly during early postnatal periods of life. The neurobiological mechanisms preceding and underlying these developmental cognitive and behavioral impairments are, however, not clearly understood. Recent evidence using animal models for monogenic NDDs demonstrates the existence of time-regulated windows of neuronal and synaptic impairments. We propose that these developmentally… CONTINUE READING
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