Sensitive thyrotropin assays: analytic and clinical performance criteria.

@article{Klee1988SensitiveTA,
  title={Sensitive thyrotropin assays: analytic and clinical performance criteria.},
  author={George G. Klee and Ian D. Hay},
  journal={Mayo Clinic proceedings},
  year={1988},
  volume={63 11},
  pages={1123-32}
}
Thyrotropin (TSH) measurements in serum traditionally have been used for the diagnosis and management of hypothyroidism; the availability of highly sensitive TSH assays has expanded the utility of these measurements to include detection of hyperthyroidism, monitoring of thyroxine replacement therapy, and front-line assessment of thyroid function. The analytic advancement that has expanded TSH utility is the noncompetitive "sandwich" immunoassay, which is faster and more sensitive than… CONTINUE READING