Sensitive point-of-care monitoring of cardiac biomarker myoglobin using aptamer and ubiquitous personal glucose meter.

@article{Wang2015SensitivePM,
  title={Sensitive point-of-care monitoring of cardiac biomarker myoglobin using aptamer and ubiquitous personal glucose meter.},
  author={Qing Wang and Fang Liu and Xiaohai Yang and Kemin Wang and Hui Wang and Xin Deng},
  journal={Biosensors & bioelectronics},
  year={2015},
  volume={64},
  pages={161-4}
}
Myoglobin (Myo), which is one of the early markers to increase after acute myocardial infarction (AMI), plays a major role in urgent diagnosis of cardiovascular diseases. Hence, monitoring of Myo in point-of-care is fundamental. Here, a novel assay for sensitive and selective detection of Myo was introduced using a personal glucose meter (PGM) as readout. In the presence of Myo, the anti-Myo antibody immobilized on the surface of polystyrene microplate could capture the target Myo. Then the… CONTINUE READING