Sensitive measurement of unmethylated repeat DNA sequences by end-specific PCR.

Abstract

We describe a new method that is well-suited for the determination of the methylation level of repetitive sequences such as human Alu elements. We have applied the method to the analysis of cell and tissue DNAs and expect it to have wide utility in studies of DNA methylation in cancer and other disease states, in monitoring response to epigenetic cancer… (More)
DOI: 10.2144/000113494

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