Sensitive detection of circulating breast cancer cells by reverse-transcriptase polymerase chain reaction of maspin gene.

@article{Luppi1996SensitiveDO,
  title={Sensitive detection of circulating breast cancer cells by reverse-transcriptase polymerase chain reaction of maspin gene.},
  author={Mario Luppi and Monica Morselli and Elena Bandieri and Massimo Federico and Roberto Marasca and Patrizia Barozzi and Maria Grazia Ferrari and M Savarino and Antonio Frassoldati and Giuseppe Torelli},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={1996},
  volume={7 6},
  pages={619-24}
}
BACKGROUND Maspin, a recently identified protein related to the family of serpins, is believed to play a role in human breast cancer. In an effort to improve the present methods of detection, we have developed a reverse-transcriptase polymerase chain reaction (RT-PCR) assay for maspin transcript to identify small numbers of mammary carcinoma cells in the… CONTINUE READING