Sensitive detection of DNA methylation.

  title={Sensitive detection of DNA methylation.},
  author={Susan E. Cottrell and Peter W. Laird},
  journal={Annals of the New York Academy of Sciences},
In recent years, many molecular biomarkers have been discovered that are capable of distinguishing tumors from normal tissue. Among the different types of markers, DNA methylation markers stand out for their potential to provide a unique combination of specificity, sensitivity, high information content, and applicability to a wide variety of clinical specimens. Methylation markers are particularly suited for situations where sensitive detection is necessary, such as when tumor DNA is either… CONTINUE READING

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