Sensitive bifunctional aptamer-based electrochemical biosensor for small molecules and protein.


In this paper, a bifunctional electrochemical biosensor for highly sensitive detection of small molecule (adenosine) or protein (lysozyme) was developed. Two aptamer units for adenosine and lysozyme were immobilized on the gold electrode by the formation of DNA/DNA duplex. The detection of adenosine or lysozyme could be carried out by virtue of switching… (More)
DOI: 10.1021/ac901727z


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