Sensitive and specific photometric determination of mannitol in human serum.

@article{Graefe2003SensitiveAS,
  title={Sensitive and specific photometric determination of mannitol in human serum.},
  author={Hendrik Graefe and Barbara G{\"u}tschow and Hartmut Gehring and Leif Dibbelt},
  journal={Clinical chemistry and laboratory medicine},
  year={2003},
  volume={41 8},
  pages={
          1049-55
        }
}
Mannitol is an osmotically active polyalcohol often present in fluids used for irrigation of exposed tissue during minimal invasive surgery. Since this polyol normally is not detected in human plasma to any significant extent, it may be used as a laboratory marker of absorption of mannitol-containing irrigative fluids during surgery. For this aim, we developed a photometric assay of mannitol in human blood or serum that may be performed in a near-patient setting. Following deproteinization of… CONTINUE READING

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