Sensitive and specific immunoassays to detect rabbit IL-8 and MCP-1: cytokines that mediate leukocyte recruitment to the lungs.

@article{Kajikawa1996SensitiveAS,
  title={Sensitive and specific immunoassays to detect rabbit IL-8 and MCP-1: cytokines that mediate leukocyte recruitment to the lungs.},
  author={Osamu Kajikawa and Richard B. Goodman and Mary Esther Cynthia Johnson and Kyoko Konishi and Thomas R. Martin},
  journal={Journal of immunological methods},
  year={1996},
  volume={197 1-2},
  pages={19-29}
}
The alpha- and beta-chemokines such as IL-8 and MCP-1 direct the recruitment of neutrophils and monocytes into the lungs and other tissues. In order to study the roles of IL-8 and MCP-1 in animals models, specific reagents are required that provide accurate measurements of these cytokines in biological fluids. Here we describe the development of sensitive and specific immunoassays for rabbit IL-8 and rabbit MCP-1, and the validation of these assays in rabbit plasma and bronchoalveolar lavage… CONTINUE READING
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