Sensitive Detection of Plasmodium vivax Using a High-Throughput, Colourimetric Loop Mediated Isothermal Amplification (HtLAMP) Platform: A Potential Novel Tool for Malaria Elimination.

@article{Britton2016SensitiveDO,
  title={Sensitive Detection of Plasmodium vivax Using a High-Throughput, Colourimetric Loop Mediated Isothermal Amplification (HtLAMP) Platform: A Potential Novel Tool for Malaria Elimination.},
  author={Sumudu Britton and Qin Cheng and Matthew J Grigg and Catherine B. Poole and Cielo Pasay and Timothy William and Kimberley Fornace and Nicholas M Anstey and Colin J. Sutherland and Christopher J. Drakeley and James S McCarthy},
  journal={PLoS neglected tropical diseases},
  year={2016},
  volume={10 2},
  pages={
          e0004443
        }
}
INTRODUCTION Plasmodium vivax malaria has a wide geographic distribution and poses challenges to malaria elimination that are likely to be greater than those of P. falciparum. Diagnostic tools for P. vivax infection in non-reference laboratory settings are limited to microscopy and rapid diagnostic tests but these are unreliable at low parasitemia. The development and validation of a high-throughput and sensitive assay for P. vivax is a priority. METHODS A high-throughput LAMP assay targeting… CONTINUE READING
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