Sensitisation of spinal cord pain processing in medication overuse headache involves supraspinal pain control

@article{Perrotta2010SensitisationOS,
  title={Sensitisation of spinal cord pain processing in medication overuse headache involves supraspinal pain control},
  author={A. Perrotta and M. Serrao and G. Sandrini and R. Burstein and G. Sances and P. Rossi and M. Bartolo and F. Pierelli and G. Nappi},
  journal={Cephalalgia},
  year={2010},
  volume={30},
  pages={272 - 284}
}
  • A. Perrotta, M. Serrao, +6 authors G. Nappi
  • Published 2010
  • Medicine
  • Cephalalgia
  • Medication overuse could interfere with the activity of critical brain regions involved in the supraspinal control of pain signals at the trigeminal and spinal level, leading to a sensitisation phenomenon responsible for chronic pain. We hypothesised that medication-overuse headache (MOH) patients might display abnormal processing of pain stimuli at the spinal level and defective functioning of the diffuse noxious inhibitory controls. We tested 31 MOH patients before (bWT) and after (aWT… CONTINUE READING

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