Sensing the Heat Stress by Mammalian Cells

Abstract

BACKGROUND The heat-shock response network controls the adaptation and survival of the cell against environmental stress. This network is highly conserved and is connected with many other signaling pathways. A key element of the heat-shock network is the heat-shock transcription factor-1 (HSF), which is transiently activated by elevated temperatures. HSF… (More)
DOI: 10.1186/2046-1682-4-16

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