Sensing the Difference: The Influence of Anisotropic Cues on Cell Behavior

@inproceedings{BallesterBeltrn2015SensingTD,
  title={Sensing the Difference: The Influence of Anisotropic Cues on Cell Behavior},
  author={Jos{\'e} Ballester-Beltr{\'a}n and Manus J. P. Biggs and Matthew J. Dalby and Manuel Salmer{\'o}n-S{\'a}nchez and Aldo Leal-Ega{\~n}a},
  booktitle={Front. Mater.},
  year={2015}
}
From tissue morphogenesis to homeostasis, cells continuously experience and respond to physical, chemical and biological cues commonly presented in gradients. In this article we focus our discussion on the importance of nano/micro topographic cues on cell activity, and the role of anisotropic milieus play on cell behavior, mostly adhesion and migration. We present the need to study physiological gradients in vitro. To do this, we review different cell migration mechanisms and how adherent cells… CONTINUE READING
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