Sensing a bud in the yeast morphogenesis checkpoint: a role for Elm1

@inproceedings{Kang2016SensingAB,
  title={Sensing a bud in the yeast morphogenesis checkpoint: a role for Elm1},
  author={Hui Kang and Denis Tsygankov and Daniel J. Lew},
  booktitle={Molecular biology of the cell},
  year={2016}
}
Bud formation by Saccharomyces cerevisiae must be coordinated with the nuclear cycle to enable successful proliferation. Many environmental stresses temporarily disrupt bud formation, and in such circumstances, the morphogenesis checkpoint halts nuclear division until bud formation can resume. Bud emergence is essential for degradation of the mitotic inhibitor, Swe1. Swe1 is localized to the septin cytoskeleton at the bud neck by the Swe1-binding protein Hsl7. Neck localization of Swe1 is… CONTINUE READING