Sensation-seeking: Dopaminergic modulation and risk for psychopathology

  title={Sensation-seeking: Dopaminergic modulation and risk for psychopathology},
  author={Agnes Norbury and Masud Husain},
  journal={Behavioural Brain Research},
Sensation-seeking (SS) is a personality trait that refers to individual differences in motivation for intense and unusual sensory experiences. It describes a facet of human behaviour that has direct relevance for several psychopathologies associated with high social cost. Here, we first review ways of measuring SS behaviour in both humans and animals. We then present convergent evidence that implicates dopaminergic neurotransmission (particularly via D2-type receptors) in individual differences… CONTINUE READING
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