Senescent heart compared with pressure overload-induced hypertrophy.

  title={Senescent heart compared with pressure overload-induced hypertrophy.},
  author={Patrick Assayag and Dani{\'e}le Charlemagne and Jo{\"e}l de Leiris and Francois R. Boucher and P E Val{\'e}re and Sylviane Lortet and Bernard Swynghedauw and Sophie Besse},
  volume={29 1 Pt 1},
Although systolic left ventricular (LV) function is normal in the elderly, aging is associated in rat papillary muscle with mechanical and sarcoplasmic reticulum Ca2+ ATPase alterations similar to those observed in the hypertrophied heart. However, alterations in the other calcium-regulating proteins implicated in contraction and relaxation are still… CONTINUE READING