Semisoluble aminated glucan: long-term efficacy against an intraperitoneal E. coli challenge and its effect on formation of abdominal adhesions.

@article{Almdahl1987SemisolubleAG,
  title={Semisoluble aminated glucan: long-term efficacy against an intraperitoneal E. coli challenge and its effect on formation of abdominal adhesions.},
  author={Sven Martin Almdahl and Rolf Seljelid},
  journal={Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie},
  year={1987},
  volume={187 5},
  pages={369-77}
}
The first part of this study in the rat was designed to assess the immediate and, in particular, the long-term effects of semisoluble aminated glucan (SAG) with regard to an intraperitoneal (i.p.) E. coli challenge and side-effects. The severity of the E. coli peritonitis was evaluated by quantification of the concomitant bacteremia. The animals randomly received either 10 ml normal saline i.p. (controls) or 10 ml (50 mg) SAG i.p. (experimental groups). It was found that SAG had no immediate… CONTINUE READING