Semiparametric models and inference for biomedical time series with extra-variation.

@article{Iannaccone2001SemiparametricMA,
  title={Semiparametric models and inference for biomedical time series with extra-variation.},
  author={Roberto Iannaccone and Stuart Coles},
  journal={Biostatistics},
  year={2001},
  volume={2 3},
  pages={
          261-76
        }
}
Biomedical trials often give rise to data having the form of time series of a common process on separate individuals. One model which has been proposed to explain variations in such series across individuals is a random effects model based on sample periodograms. The use of spectral coefficients enables models for individual series to be constructed on the basis of standard asymptotic theory, whilst variations between individuals are handled by permitting a random effect perturbation of model… CONTINUE READING