Semiology and Mechanisms of Near-Death Experiences

  title={Semiology and Mechanisms of Near-Death Experiences},
  author={Costanza Peinkhofer and Jens P. Dreier and Daniel Kondziella},
  journal={Current Neurology and Neuroscience Reports},
Near-death experiences (NDEs) are conscious perceptual experiences, including self-related emotional, spiritual, and mystical experiences, occurring in close encounters with death or in non-life-threatening situations. The origin of NDEs remains unknown. Here, we review recent advances in the understanding of NDE semiology and pathophysiology. Recent prospective studies confirm that NDEs reflect a spectrum of highly distinctive memories which are associated with negative or positive emotions… 
Near-Death Experience as a Probe to Explore (Disconnected) Consciousness
Losing the Self in Near-Death Experiences: The Experience of Ego-Dissolution
This study suggests that the experience of dissolved ego-boundaries is a common feature of NDEs and is positively correlated with the intensity of OBE and a sense of unity.
The Neurology of Death and the Dying Brain: A Pictorial Essay
The aim is to provide the reader with a thorough understanding that the boundaries within the neurology of death and the dying brain are being pushed just like everywhere else in the clinical neurosciences.
Migraine aura, a predictor of near-death experiences in a crowdsourced study.
In this sample, migraine aura was a predictor of near-death experiences, which indirectly supports the association between NDE and REM intrusion and might have implications for the understanding of NDE.
Migraine aura, a predictor of near-death experiences in a crowdsourced study
In this sample, migraine aura was a predictor of NDE, which indirectly supports the association between NDE and REM intrusion and might have implications for the understanding ofNDE.
The evolutionary origin of near-death experiences: a systematic investigation
It is proposed that the acquisition of language enabled humans to transform these events from relatively stereotyped death-feigning under predatory attacks into the rich perceptions that form near-death experiences and extend to non-predatory situations.
Prevalence of near-death experiences in people with and without REM sleep intrusion
While age, gender, place of residence, employment status and perceived threat do not seem to influence the prevalence of near-death experiences, a possible association with REM sleep intrusion is confirmed.
Cortical Inhibitory Imbalance in Functional Paralysis
This study extends current knowledge of functional weakness, arguing for a specific central nervous system abnormality which may be involved in the symptoms’ pathophysiology.
The Development of a Quantum-based Ontology for the Description of the Reality Experienced in NDEs by Using Computerized NLP Analytics
According to the survival hypothesis, a person's personality and consciousness survive the death of the physical body. Ontology is a well-established theoretical branch of philosophy concerned with


Biological Aspects of Near-Death Experiences
  • B. Greyson
  • Medicine, Psychology
    Perspectives in biology and medicine
  • 1998
Near-death experiences are important to physicians not only because they may occur to patients while under the authors' care, but because they often lead to profound aftereffects that may affect health and response to medical treatments.
DMT Models the Near-Death Experience
A significant overlap in nearly all of the NDE phenomenological features is found when comparing DMT-induced NDEs with a matched group of ‘actual’ NDE experiencers, and a striking similarity between these states that warrants further investigation is revealed.
Understanding the cognitive experience of death and the near-death experience.
  • S. Parnia
  • Psychology
    QJM : monthly journal of the Association of Physicians
  • 2017
“Reality” of near-death-experience memories: evidence from a psychodynamic and electrophysiological integrated study
The findings suggest that, at a phenomenological level, NDE memories cannot be considered equivalent to imagined memories, and at a neural level,NDE memories are stored as episodic memories of events experienced in a peculiar state of consciousness.
Near-death experiences: actual considerations.
The notion that death represents a passing to an afterlife, where we are reunited with loved ones and live eternally in a utopian paradise, is common in the anecdotal reports of people who have
False memory susceptibility in coma survivors with and without a near-death experience
Examination of NDEs’ susceptibility to false memories using the Deese–Roediger–McDermott (DRM) paradigm demonstrated that NDErs and volunteers were equally likely to produce false memories, but that Nders recalled them more frequently associated with compelling illusory recollection.
Distressing Near-Death Experiences.
The relationship of all three types to prototypical near-death experiences merits further study, and the effect of the distressing experience in the lives of individuals deserves exploration.