Seminars in thrombosis, thrombolysis and vascular biology. 3. Platelet activity in cardiovascular disease.

Abstract

Platelets contribute to normal hemostasis by adhering to subendothelial tissues after vascular damage has taken place and then recruiting additional platelets through the process of aggregation. Activation of the coagulation cascade ultimately results in fibrin deposition. In pathological conditions, thrombogenic surfaces act as a nidus for platelet… (More)

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