Seminal vesicle protein IV and its derived active peptides: a possible physiological role in seminal clotting.

@article{Metafora2007SeminalVP,
  title={Seminal vesicle protein IV and its derived active peptides: a possible physiological role in seminal clotting.},
  author={Salvatore Metafora and Carla Lucia Esposito and Ivana Caputo and Marilena Lepretti and Diana Cassese and Alessandra Dicitore and Pasquale Ferranti and Paola Stiuso},
  journal={Seminars in thrombosis and hemostasis},
  year={2007},
  volume={33 1},
  pages={53-9}
}
Seminal vesicle protein 4 (SV-IV) is a highly flexible molecule that in aqueous solution behaves as a concentration-dependent self-associating system in which the degree of association (monomer <--> dimer <--> trimer equilibrium) seems to be related to its biological activities. This review reports the functional role of SV-IV in seminal clotting exerted through the modulation of inflammation, hemostasis, and sperm protection against the damage induced by immunological or reactive oxygen… CONTINUE READING