Seminal 'priming' for protection from pre-eclampsia-a unifying hypothesis.

  title={Seminal 'priming' for protection from pre-eclampsia-a unifying hypothesis.},
  author={Sarah A Robertson and John J Bromfield and Kelton Tremellen},
  journal={Journal of reproductive immunology},
  volume={59 2},
Conventional belief holds that an immune response to ejaculate antigens should interfere with fertilisation and establishment of pregnancy. However, emerging evidence now supports the opposing view-that insemination acts to activate maternal immune mechanisms exerting a positive effect on reproductive events. In a response well documented in rodents, semen triggers an influx of antigen-presenting cells into the female reproductive tract which process and present paternal ejaculate antigens to… CONTINUE READING
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