Semiautomated procedures for evaluation of carbohydrate-deficient transferrin in the diagnosis of alcohol abuse.

@article{Bean1997SemiautomatedPF,
  title={Semiautomated procedures for evaluation of carbohydrate-deficient transferrin in the diagnosis of alcohol abuse.},
  author={Pamela Bean and K R Liegmann and Trond L\ovli and Carol E Westby and Erling Sundrehagen},
  journal={Clinical chemistry},
  year={1997},
  volume={43 6 Pt 1},
  pages={983-9}
}
Carbohydrate-deficient transferrin (CDT) may now be the most valuable biological marker for diagnosis of alcohol abuse. We compared the diagnostic performance of two new CDT tests, Axis %CDT turbidimetric immunoassay (TIA) and Axis %CDT HPLC, against Specialty Laboratories' isoelectric focusing/immunoblotting/laser densitometry (IEF/IB/LD). Both Axis tests include one-half the concentration of trisialotransferrin isoforms in their CDT quantitation schemes. Considering an alcohol abuse… CONTINUE READING

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