Semiautomated method for analysis of enteric-coated and plain coated diethylstilbestrol tablets.

@article{Kolinski1980SemiautomatedMF,
  title={Semiautomated method for analysis of enteric-coated and plain coated diethylstilbestrol tablets.},
  author={R E Kolinski and J W Myrick and E A Bunch},
  journal={Journal of pharmaceutical sciences},
  year={1980},
  volume={69 8},
  pages={951-4}
}
A semiautomated fluorometric method for the analysis of enteric-coated and plain coated diethylstilbestrol tablets is presented. To eliminate interferences from tablet excipients, diethylstilbestrol is extracted into an organic solvent and then into a basic aqueous solution. After UV irradiation, a product of diethylstilbestsrol is formed from which a fluorophore is produced chemically. The fluorescence is measured at an excitation wavelength of 335 nm and an emission wavelength of 410 nm. The… CONTINUE READING