Semi-synthetic hydrogel composition and stiffness regulate neuronal morphogenesis.

Abstract

This study describes the use of a set of protein-based biomaterials that allow us to explore the mechanism of cell-mediated 3-D invasion associated with peripheral nerve regeneration. Hydrogels made from poly(ethylene glycol) (PEG) conjugated extracellular matrix proteins, including fibrinogen, gelatin and albumin were compared in their ability to support… (More)
DOI: 10.1016/j.ijpharm.2016.11.032

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