Semi-quantitative fluorescent PCR analysis identifies PRKAA1 on chromosome 5 as a potential candidate cancer gene of cervical cancer.

@article{Huang2006SemiquantitativeFP,
  title={Semi-quantitative fluorescent PCR analysis identifies PRKAA1 on chromosome 5 as a potential candidate cancer gene of cervical cancer.},
  author={Fung Yu Huang and Pui Man Chiu and Kar Fai Tam and Yvonne Ka Yin Kwok and Elizabeth Tak-Kwong Lau and Mary Hoi-Yin Tang and Tong Yow Ng and Vincent Wing Sun Liu and Annie Nga-Yin Cheung and Hextan Yuen-Sheung Ngan},
  journal={Gynecologic oncology},
  year={2006},
  volume={103 1},
  pages={219-25}
}
OBJECTIVE Comparative genomic hybridization has frequently detected amplification of chromosome 5p in cervical cancer, but candidate cancer genes within the region are rarely known. Therefore, we pursued to identify potential candidate gene related to cervical cancer development. METHODS A series of 128 cervical tumor samples were examined by semi-quantitative fluorescent differential PCR for copy number changes on three candidate genes (PRKAA1, CTNND2 and POLS) mapped to chromosome 5p and… CONTINUE READING
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