Semi-quantification of methionine uptake and flair signal for the evaluation of chemotherapy in low-grade oligodendroglioma

@article{Tang2004SemiquantificationOM,
  title={Semi-quantification of methionine uptake and flair signal for the evaluation of chemotherapy in low-grade oligodendroglioma},
  author={Bich-Ngoc-Thanh Tang and Niloufar Sadeghi and Fabrice Branle and Olivier De Witte and David Wikler and Serge Goldman},
  journal={Journal of Neuro-Oncology},
  year={2004},
  volume={71},
  pages={161-168}
}
11C-Methionine (MET) is a useful positron emission tomography (PET) tracer for the evaluation of low-grade gliomas. Among these tumors, a high percentage of low-grade oligodendrogliomas (ODG) are sensitive to chemotherapy with procarbazine, CCNU, and vincristine (PCV). We aimed at: (1) objectively assessing ODG response to PCV by a metabolic index (the Activity Volume Index or AVI) generated from an automated semi-quantification of PET with MET (PET-MET); (2) comparing AVI and quantitative… CONTINUE READING