Semi-continuous production of the antibiotic patulin by immobilized cells of Penicillium urticae

@article{Deo2004SemicontinuousPO,
  title={Semi-continuous production of the antibiotic patulin by immobilized cells of Penicillium urticae},
  author={Yashwant M. Deo and Genevi{\`e}ve Gaucher},
  journal={Biotechnology Letters},
  year={2004},
  volume={5},
  pages={125-130}
}
Conidia of Penicillium urticae, immobilized in κ-carrageenan beads, were germinated in situ to form a patulin producing cell mass by incubating these beads in a growth supporting medium. When these in situ grown immobilized cells were repeatedly transferred and incubated in a nitrogen-free production medium they exhibited a greater than three fold increase in the half-life of patulin production as compared with similarly treated free cells. When conidia were first germinated and grown to form a… CONTINUE READING

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GrootWassink, J.W.D. and G.M

  • G. M. Gaucher, K. S. Lam, J.W.D. GrootWassink, J. Neway, Y. M. Deo
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