Semaphorin 4D expression is associated with a poor clinical outcome in cervical cancer patients.


Lymphangiogenesis is thought to be essential for cancer progression, making it an important target in cancer therapy. Lymphangiogenic factors (VEGF-C and VEGF-D) are upregulated in various tumors/cancers, and play an important role in lymphangiogenesis and lymph node metastasis. Similarly, semaphorin 4D (Sema4D) is a potent inducer of angiogenesis, and its… (More)
DOI: 10.1016/j.mvr.2014.02.007