Semaphorin 3A alters endothelial cell immunogenicity by regulating Class II transactivator activity circuits.

@article{Schlahsa2014Semaphorin3A,
  title={Semaphorin 3A alters endothelial cell immunogenicity by regulating Class II transactivator activity circuits.},
  author={Laura Schlahsa and Haijiao Zhang and Anja Battermann and Murielle Verboom and Stephan Immenschuh and Britta Eiz-Vesper and Renata Stripecke and Katrin Engelmann and Rainer Blasczyk and Constança Figueiredo},
  journal={Transfusion},
  year={2014},
  volume={54 8},
  pages={1961-70}
}
BACKGROUND Endothelial cells (ECs) play a pivotal role in the allogeneic immune response upon transplantation. Semaphorin 3A (Sema3A) was implicated in the modulation of EC growth, but its effects on immunogenicity were not previously investigated. STUDY DESIGN AND METHODS ECs were transduced with a lentiviral vector encoding for the green fluorescence… CONTINUE READING