Selfish DNA and the origin of introns

@article{Cavaliersmith1985SelfishDA,
  title={Selfish DNA and the origin of introns},
  author={T Cavalier-smith},
  journal={Nature},
  year={1985},
  volume={315},
  pages={283-284}
}
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ncbi.nlm.nih.gov
196 Citations
Highly Influential Citations
3
Background Citations
55
Methods Citations
2
Results Citations
3

196 Citations

A novel intron site in the triosephosphate isomerase gene from the mosquito Culex tarsalis
TLDR
The TPI gene from the mosquito, Culex tarsalis, contains an intron in a unique position that was predicted by W. Gilbert2 and the exon shuffling hypothesis, and is found to be consistent with the 'introns late' view.
The Origin and Function of Intervening Sequences in DNA: A Review
TLDR
Current data support the second view, suggesting that although introns have played an important role in the evolution of new functional proteins, this role cannot be seen as an adaptation, at least at the level of organisms within a species.
Human Transaldolase-associated Repetitive Elements Are Transcribed by RNA Polymerase III*
TLDR
The results suggest RNA polymerase III-mediated transcription of TARE may be a source of repetitive elements, contributing to distinct genes and thus shaping the human genome.
Reverse Transcriptase Activities in Mycelial Fungi
TLDR
Reverse transcriptases (RT) are RNA-dependent DNA polymerases which were discovered in retroviruses more than 20 years ago and have been designated retroelements mainly on their sequence similarity to retroviral reverse transcriptases.
Towards a reconciliation of the introns early or late views: triosephosphate isomerase genes from insects.
On the concept of biological function, junk DNA and the gospels of ENCODE and Graur et al.
TLDR
An old hypothesis on the evolution of genome size and on the role of so called ‘junk DNA’ (jDNA), which might explain C-value enigma is brought forward.
Correlation of intron-exon organisation with the three-dimensional structure in glutamate dehydrogenase.
Origins and Evolutionary Relationships of Retroviruses
TLDR
Computer alignment of all these sequences allows an overall phylogeny to be constructed that chronicles the history of events leading to infectious retroviruses.
The signal of ancient introns is obscured by intron density and homolog number
TLDR
This finding matches the expectation of the mixed model of intron origin, in which a fraction of phase zero introns are left from the assembly of the first genes, while other introns have been added in the course of evolution.
An ancient group I intron shared by eubacteria and chloroplasts
TLDR
The homology of the intron across chloroplasts and cyanobacteria implies that it was present in their common ancestor and that it has been maintained in their genomes for at least 1 billion years.
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