• Corpus ID: 33802670

Selfish DNA: a sexually-transmitted nuclear parasite.

@article{Hickey1982SelfishDA,
  title={Selfish DNA: a sexually-transmitted nuclear parasite.},
  author={Donal A Hickey},
  journal={Genetics},
  year={1982},
  volume={101 3-4},
  pages={
          519-31
        }
}
  • D. Hickey
  • Published 1 July 1982
  • Biology
  • Genetics
A quantitative population genetics model for the evolution of transposable genetic elements is developed. This model shows that "selfish" DNA sequences do not have to be selectively neutral at the organismic level; indeed, such DNA can produce major deleterious effects in the host organism and still spread through the population. The model can be used to explain the evolution of introns within eukaryotic genes; this explanation does not invoke a long-term evolutionary advantage for introns, nor… 

Tables from this paper

PERSPECTIVE: TRANSPOSABLE ELEMENTS, PARASITIC DNA, AND GENOME EVOLUTION
TLDR
It is argued that easy popular appellations such as “selfish DNA’ and “junk DNA” may be either inaccurate or misleading and that a more enlightened view of the transposable element‐host relationship encompasses a continuum from extreme parasitism to mutualism.
Evolutionary dynamics of transposable elements in prokaryotes and eukaryotes
TLDR
It is argued that the pattern of sexual outbreeding seen in mammals and plants is especially favorable to the spread of transposons and that the evolutionary origin of sexual conjugation may have been due to selection on transposon-encoded genes.
Evolutionary Dynamics of Transposable Elements in Prokaryotes and Eukaryotes
TLDR
It is argued that the pattern of sexual outbreeding seen in mammals and plants is especially favorable to the spread of transposons and that the evolutionary origin of sexual conjugation may have been due to selection on transposon-encoded genes.
Selfish Genetic Elements Favor The Evolution of a Distinction Between Soma and Germline
  • L. J. Johnson
  • Biology
    Evolution; international journal of organic evolution
  • 2008
TLDR
This work model the evolutionary success of a selfish element, such as a transposable element or endosymbiont, which is capable of creating or strengthening a germline-soma distinction in a primitively multicellular host, and finds that it will always benefit the element to do so.
Transposable element-medicated evolution of sex: A population genetic model
TLDR
The analysis is extended to include the possibility that the transposable element can modulate the probability of sexual reproduction, thus casting Hickey’s (1982,Genetics 101: 519–531) suggestion in a population genetics framework.
Symbiotic DNA in eukaryotic genomes.
Mobile DNA can drive lineage extinction in prokaryotic populations
TLDR
This study uses a range of epidemiological and ecological models to show that harmful mobile DNA can invade, and drive populations to extinction, provided their transmission rate is high and that mobile element‐induced mortality is not too high.
Deleterious transposable elements and the extinction of asexuals.
TLDR
The genomes of virtually all sexually reproducing species contain transposable elements, and the ability of sex, despite facilitating the spread of deleterious elements within interbreeding populations, also to restrain their intragenomic proliferation is an important component of the evolutionary advantage of sex over asex.
Population dynamics of gene transfer
...
1
2
3
4
5
...

References

SHOWING 1-8 OF 8 REFERENCES
How selfish is DNA?
TLDR
Two articles using the term ‘Selfish DNA’ to describe certain DNA sequences in eukaryotic organisms argued that the process of DNA replication allows the accumulation within the replicating genome of DNA sequences which have no functional (phenotypic) significance but whose presence stimulates the further accumulation of sequences of the same kind.
Meiotic Drive as an Evolutionary Force
TLDR
Some of the consequences of meiotic drive on the genetic structure of natural populations, including those of man, and its evolutionary implications are considered.
Nuclear volume control by nucleoskeletal DNA, selection for cell volume and cell growth rate, and the solution of the DNA C-value paradox.
TLDR
Eukaryote DNA can be divided into genic DNA, which codes for proteins (or serves as recognition sites for proteins involved in transcription, replication and recombination), and nucleoskeletal DNA (S-DNA), which exists only because of its nucleoskeleton role in determining the nuclear volume.
Sequence and organization of the human mitochondrial genome
TLDR
The complete sequence of the 16,569-base pair human mitochondrial genome is presented and shows extreme economy in that the genes have none or only a few noncoding bases between them, and in many cases the termination codons are not coded in the DNA but are created post-transcriptionally by polyadenylation of the mRNAs.
Implications of RNA-RNA splicing in evolution of eukaryotic cells.
TLDR
The recently discovered noncontiguous sequences in eukaryotic DNA that encode messenger RNA may reflect an ancient, rather than a new, distribution of information in DNA and that eukARYotes evolved independently of prokaryotes.
Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis
TLDR
The data indicate that, as a rare event, the ALV provirus integrates adjacent to the c-myc gene and that transcription, initiating from a viral promoter, causes enhanced expression of c- myc, leading to neoplastic transformation.
Evolution of sex
The Economy of Nature and the Evolution of Sex*. By Michael T. Ghiselin. Pp. xii + 346. (University of California: Berkeley, Los Angeles and London, December 1974.) $12.05; £7.10.