Selfish DNA: Homing Endonucleases Find a Home

@article{Edgell2009SelfishDH,
  title={Selfish DNA: Homing Endonucleases Find a Home},
  author={David R. Edgell},
  journal={Current Biology},
  year={2009},
  volume={19},
  pages={R115-R117}
}
  • D. R. Edgell
  • Published 10 February 2009
  • Medicine, Biology
  • Current Biology
Self-splicing group I introns come in two flavours - those with a homing endonuclease to promote mobility of the intron, and those without an endonuclease. How homing endonucleases and self-splicing introns associate to form a composite selfish genetic element is a question of long-standing interest. Recent work has revealed that a shared characteristic of both introns and endonucleases, the targeting of conserved sequences, may provide the impetus for the evolution of composite mobile genetic… 

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TLDR
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