Selfish DNA: Homing Endonucleases Find a Home

Abstract

Self-splicing group I introns come in two flavours - those with a homing endonuclease to promote mobility of the intron, and those without an endonuclease. How homing endonucleases and self-splicing introns associate to form a composite selfish genetic element is a question of long-standing interest. Recent work has revealed that a shared characteristic of… (More)
DOI: 10.1016/j.cub.2008.12.019

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